Spinal Cord Injury Overview

A spinal cord injury (SCI) is an injury to the spinal cord resulting in a change, either temporary or permanent, in the cord’s normal motor, sensory, or autonomic function.

Common causes of damage are trauma (car accident, gunshot, falls, sports injuries, etc.) or disease (transverse myelitis, polio, spina bifida, Friedreich’s ataxia, etc.). The spinal cord does not have to be severed in order for a loss of function to occur.

Link to Spinal Cord Injury Hub

Initial Overview based on Wikipedia entry Jan. 4, 2016.

Regeneration of Neurons by Cancer Drug

In animal studies, the cancer drug epothilone reduced the formation of scar tissue in injuries to the spinal cord and stimulated growth in damaged nerve cells.

Epothilone is able to inhibit directional movement in scar-forming cells while stimulating active growth in nerve cell axons. The animals treated with epothilone after spinal cord injury walked better than those that received no treatment,

Science 3/12/15

Neuroprosthetics for paralysis: a new implant on the spinal cord

New therapies are on the horizon for individuals paralyzed following spinal cord injury.

The e-Dura implant developed by EPFL scientists can be applied directly to the spinal cord without causing damage and inflammation. The device is described in an article appearing online. Science 1/8/15

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