Washington University Neuroscience

The Washington University Neuroscience Program offers outstanding neuroscience education for Ph.D. students and exciting research opportunities for Postdoctoral scientists.

The Program includes a broad spectrum of research laboratories that study how the brain works. Neuroscience research has included the nobel-prize winning insights of Rita Levi-Montalcini and Viktor Hamburger on formation and development of the nervous sytem, through development of Positron Emission Tomography (PET) imaging, to current innovations in detection and treatment of Alzheimer's Disease.

Early Cancer Detection with Photoacoustic Tomography

"Clinical applications of PAT include imaging of parameters associated with cancer, offering the prospect of earlier detection."

His laboratory invented or discovered functional photoacoustic tomography, 3D photoacoustic microscopy (PAM). PAM broke through the long-standing diffusion limit to the penetration of conventional optical microscopy and reached super-depths for noninvasive biochemical, functional, and molecular imaging in living tissue at high resolution.

Video published on June 29, 2012 by SPIETV

Optical Imaging Laboratory – Washington U

Principal Investigator: Lihong Wang
Washington University Neuroscience Program

Optical Imaging Laboratory develops novel biophotonic tomography for early-cancer detection and functional imaging, using non-ionizing electromagnetic and ultrasonic waves. Research directions include: Photo-acoustic tomography (PAT), Thermo-acoustic tomography (TAT), Ultrasound-modulated (acousto-) optical tomography (UOT), Mueller optical-coherence tomography (M-OCT), Oblique-incidence reflectometry (OIR) and spectroscopy, and Modeling light transport in tissues.

Lihong Wang, PhD – Washington U

Professor of Biomedical Engineering, Washington University
Director, Optical Imaging Laboratory

His lab reported the first functional photoacoustic tomography, 3D photoacoustic microscopy (PAM), optical-resolution PAM, photoacoustic Doppler effect, photoacoustic reporter gene imaging, microwave-induced thermoacoustic tomography, the universal photoacoustic reconstruction algorithm, frequency-swept ultrasound-modulated optical tomography, time-reversed ultrasonically encoded (TRUE) optical focusing, sonoluminescence tomography, Mueller-matrix optical coherence tomography, and optical coherence computed tomography.

Deep Photoacoustic Tomography

Principal Investigator: Lihong Wang
Washington University
Title: "Fast High-Resolution Deep Photoacoustic Tomography of Action Potentials in Brains"
BRAIN Category: Large-Scale Recording-Modulation - New Technologies (RFA NS-14-007)

Dr. Wang and his collaborators will test a way to image the electrical activity of neurons deep inside the brain, using a variation on ultrasound imaging he invented called photoacoustic tomography.

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