Neuroscience Discovery Institute @JHU

The mission of the new Kavli Neuroscience Discovery Institute (Kavli NDI) at JHU is to bring together neuroscientists, engineers and data scientists to investigate neural development, neuronal plasticity, perception and cognition.

The Kavli Foundation award is a tremendous honor, because it allows Johns Hopkins to build on our history of pioneering neuroscience and catalyze new partnerships with engineers and data scienctists that will be essential to building a unified understanding of brain function,” said Johns Hopkins University President Ronald J. Daniels.

John Hopkins Neuroscience

John Hopkins has two primary centers for neuroscience research: The Solomon Snyder Department of Neuroscience in the School of Medicine and the Department of Psychological and Brain Sciences in the School of Arts & Sciences.

Current research ranges from investigating the development of the nervous system, synaptic plasticity and the molecular and cellular mechanisms of learning and memory to the neural basis of higher brain function such as perception and decision-making.

Researching human spatial recognition

"Researching human spatial recognition"
Science Nation - April 2, 2014

With funding from the National Science Foundation, Amy Shelton is testing human spatial recognition. Study subjects learn and recall their way around a virtual maze while an MRI scans their brains. By analyzing MRI images of blood flow in the human Shelton can get a picture of how the brain learns and recalls the spatial world outside the body.

Richard Huganir, PhD – John Hopkins

Professor and Director of the Department of Neuroscience at Johns Hopkins University; Co-Director, Brain Science Institute; and HHMI investigator.
Member of Multi-Council Working Group (NIMH council)

Huganir's lab is credited for examining the molecular mechanisms underlying the regulation of neurotransmitter receptor function with a focus on glutamate receptors. Their studies have suggested that regulation of receptor function may be a major mechanism for the regulation of synaptic plasticity in the nervous system in health and disease.

NIH Neuroscience Seminar- April 13, 2015

TITLE: Mechanisms of ubiquitin signaling in gene regulation and chromatin dynamics

AUTHOR: Cynthia Wolberger, Ph.D., Johns Hopkins University

TIME: 12:00:00 PM DATE: Monday, April 13, 2015

PLACE: Porter Neuroscience Research Center

Live NIH Videocast (archived after seminar)

Section of High Resolution Brain PET Imaging

Director: Dean Foster Wong
John Hopkins School of Medicine

John Hopkins neuroimaging specialists will develop a noninvasive way of measuring human brain neuronal activity and chemical changes in milliseconds as opposed to several minutes, as in current PET scans. The new technique will also be much more sensitive to neurochemical processes than other imaging techniques, including functional magnetic resonance imaging and magnetoencephalographic recording of brain magnetic fields

Dean Foster Wong, MD/PhD – JHU

Professor, Johns Hopkins Medicine Department of Radiology and Radiological Science
Radiology Vice Chair, Research Administration and Training
Director Section of High Resolution Brain PET Imaging, Division of Nuclear Medicine

Dr. Wong has used PET scanning to uncover key insights into brain chemistry and to identify receptors for the major neurotransmitters. He oversaw the first dopamine PET receptor imaging in human beings; led the first study suggesting D2 dopamine receptors in schizophrenia, and how dopamine is transported in and out of cells.

Imaging in vivo neurotransmitter modulation

Principal Investigator: Dean Foster Wong
Johns Hopkins University
Title: Imaging in vivo neurotransmitter modulation of brain network activity in realtime
BRAIN Category: Next Generation Human Imaging (RFA MH-14-217)

Dr. Wong and colleagues will explore the possibility that newly developed infrared chemical tags may be used for minimally invasive imaging of rapidly changing human brain chemical messenger activity – with greater time resolution.

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