Mark Steyvers, PhD – UC Irvine

Professor, Cognitive Sciences UC Irvine
Principal Investigator, Memory and Decision Laboratory

Dr. Steyvers research focuses on Wisdom of Crowds; Aggregating human judgments; Computational models of the mind; Machine Learning and Statistics; Memory and Decision Making.

UC Irvine Neuroscience

UC Irvine's neuroscience efforts are primarily focused on the Department of Anatomy & Neurobiology in the School of Medicine and the Department of Neurobiology and Behavior in the School of Biological Sciences.

Research projects aim to discover treatments and cures for epilepsy, Alzheimer’s disease, stroke, learning and memory disorders, drug addiction, ALS (Lou Gehrig’s disease), deafness and other hearing disorders, spinal cord injury, Parkinson’s disease, dementia, mental retardation and to learn more about systems neuroscience, learning and memory, cell signaling, and hearing research.

Soltesz Lab: GABAergic interneurons in the hippocampus

"How GABAergic interneurons in the hippocampus choose their postsynaptic partners"

The CA1 region consists of heterogeneous pyramidal cells. In this video, Drs. Ivan Soltesz, Sang-Hun Lee, and Ivan Marchionni describe that GABAergic, parvalbumin expressing basket cells preferentially target specific subsets of pyramidal cells, while being selectively excited by other subsets, demonstrating nonuniform perisomatic inhibition of hippocampal output channels.

Thinking Brain – Mysteries of the Brain

"Through neural connections, called synapses, the brain can process and store enormous amounts of information. Neuroscientist Gary Lynch at the University of California, Irvine explains how this incredibly complex communication process allows animals to learn and remember."

"Mysteries of the Brain" is produced by NBC Learn in partnership with the NSF.

NSF BRAIN Initiative
Published June 10, 2015

Soltesz Lab – UCIrvine

Principal Investigator: Ivan Soltesz
UC Irvine Neuroscience

The Soltesz Lab is interested in how brain cells communicate with each other and how the communication changes after fever-induced seizures in early childhood and after head injury. Our general goal is to understand how neuronal networks function and dysfunction, in order to discover new therapies to prevent epilepsy.

Ivan Soltesz, PhD – UC Irvine

Professor & Chair: Anatomy & Neurobiology, Physiology & Biophysics, and Neurobiology & Behavior
Director, Soltesz Lab

Research Focus: Working to understand: traumatic brain injury, post-traumatic epilepsy, fever-induced (Febrile) seizures in childhood, learning and memory deficits.

Scientific Focus: functions, development and plasticity of hippocampal interneuronal networks. Physiological basis of hyperexcitability. Mechanisms of selective neuronal vulnerability.

David Feinberg, MD/PhD – UCSF

Adjunct professor of neuroscience at UC Berkely and of Radiology at UCSF
Board Certified Diagnostic Radiologist and Neuroradiologist
President, Advanced MRI Technologies (AMRIT)

Dr. Feinberg is an internationally recognized expert on Magnetic Resonance Imaging (MRI), with numerous publications and research studies to his credit. In addition, he holds many patents in MRI technology

Circuitry Underlying Memory replay

Principal Investigator: Ivan Soltesz
UC Irvine Neuroscience
Title: "Towards a Complete Description of the Circuitry Underlying Memory replay"
BRAIN Category: Understanding Neural Circuits (RFA NS-14-009)

Dr. Soltesz's team will combine computer brain modeling and large-scale recordings of hundreds of neurons to understand how the brain generates sharp-wave-ripples, a neuronal activity pattern essential for learning and memory.

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