BigNeuron

BigNeuron: Building consensus among automated morphological reconstructions

By Todd A. Gillette, Hanchuan Peng, Xiaoxiao Liu, Yinan Wan, Giorgio A. Ascoli

A community effort to find out what is exactly the state-of-the-art of single neuron reconstruction, standardize the protocols, and esablish a Big Data resource for neuroscience.

G Protein-binding SfN Poster

By Justin R. King1, Ming-Kuan Lin2, Nadine Kabbani

"A G protein-binding domain within the α7 nicotinic receptor enables downstream calcium signaling beyond the time course of channel activation"

α7 nicotinic acetylcholine receptors (nAChRs) play an important role in synaptic transmission via regulation of intracellular signaling pathways. In recent studies, we demonstrated an important functional role for α7 nAChR interactions with intracellular heterotrimeric GTP binding proteins (G proteins) in cell signaling.

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