Klotho delays aging & improves cognition

July 9, 2017 Scott Joy

Graphical abstract from Cell Reports May 22, 2014

Summary

Klotho is an enzyme that in humans is encoded by the KL gene. Transgenic mice that over express Klotho live longer than wild-type mice.

Klotho is a transmembrane protein that, in addition to other effects, provides some control over the sensitivity of the organism to insulin and appears to be involved in aging and cognition. Dena Dubal, UCSF, says could be ” a very new way to treat diseases ranging from Alzheimer’s to Schizoprenia”.

Journal of Neuroscience 2/11/15

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