The US Congress established the Office of Science and Technology Policy (OSTP) in 1976 with a broad mandate to advise the President and others within the Executive Office of the President on the effects of science and technology on domestic and international affairs.

OSTP with NIH is leading interagency efforts to develop and implement the BRAIN Initiative policies and budgets, and is working with the private sector, state and local governments, the science and higher education communities, and other nations toward this end.