Professor and Director of the Department of Neuroscience at Johns Hopkins University; Co-Director, Brain Science Institute; and HHMI investigator. Member of Multi-Council Working Group (NIMH council)

Huganir’s lab is credited for examining the molecular mechanisms underlying the regulation of neurotransmitter receptor function with a focus on glutamate receptors. Their studies have suggested that regulation of receptor function may be a major mechanism for the regulation of synaptic plasticity in the nervous system in health and disease.

Web Information

Department Webpage: hneuroscience.jhu.edu/resources/directory/faculty/richard-l.-huganir/

Lab Page: neuroscience.bs.jhmi.edu/huganir/

Twitter:

Contact Information

Email: rhuganir@jhmi.edu

Phone:  410-955-4050

Address: The Solomon H. Snyder Department of Neuroscience Johns Hopkins University School of Medicine 725 North Wolfe Street Baltimore, MD 21205 Room: Hunterian 1009A

Research

Regulation of Neurotransmitter Receptors and Brain Function in Health and Disease

Neurotransmitter receptors mediate signal transduction at the postsynaptic membrane of synaptic connections between neurons in the nervous system. We have been studying the molecular mechanisms in the regulation of neurotransmitter receptor function. Recently we have focused on glutamate receptors, the major excitatory receptors in the brain. Glutamate receptors can be divided into two major classes: AMPA and NMDA receptors. AMPA receptors mediate rapid excitatory synaptic transmission while NMDA receptors play important roles in neuronal plasticity and development. Studies in ...

 

The mission of the new Kavli Neuroscience Discovery Institute (Kavli NDI) at JHU is to bring together neuroscientists, engineers and data scientists to investigate neural development, neuronal plasticity, perception and cognition.

“The challenges of tomorrow will not be confined to distinct disciplines, and neither will be the solutions we create,” said Johns Hopkins University President Ronald J. Daniels. “The Kavli Foundation award is a tremendous honor, because it allows Johns Hopkins to build on our history of pioneering neuroscience and catalyze new partnerships with engineers and data scienctists that will be essential to building a unified understanding of brain function.”

 

Web Information

Kavli Foundation web page:  http://www.kavlifoundation.org/johns-hopkins-university

About Kavli NDI

The Kavli Neuroscience Discovery Institute (Kavli NDI) brings together neuroscience, engineering, and data science – three traditional strengths at Johns Hopkins – with the ultimate goal of reaching a unified understanding of brain function.

New experimental techniques are generating a wealth of information about the brain at different scales – from the levels of single cells to brain circuits to behavior – but neuroscience still lacks effective tools for managing these massive data sets. Kavli NDI researchers are filling this gap by finding new ways to organize, analyze, and extract meaning from neurodata. They plan to ...

John Hopkins has two primary centers for neuroscience research: The Solomon Snyder Department of Neuroscience in the School of Medicine and the Department of Psychological and Brain Sciences in the School of Arts & Sciences.

Current research ranges from investigating the development of the nervous system, synaptic plasticity and the molecular and cellular mechanisms of learning and memory to the neural basis of higher brain function such as perception and decision-making.

Web Information

Department of Neuroscience website: neuroscience.jhu.edu/about/contact-us/ Department of Psychological and Brain Sciences website:  pbs.jhu.edu/ Brain Initiative Grant – “Imaging in vivo neurotransmitter modulation of brain network activity in realtime”

Contact Information

Department of Neuroscience Phone: 410-614-2447 Address: The Johns Hopkins University School of Medicine Department of Neuroscience 1003 Wood Basic Science Building 725 N. Wolfe St. Baltimore, MD 21205 Director, : Rick Huganir

Department of Psychological and Brain Sciences Phone: (410) 516-7055 Address: Department of Psychological & Brain Sciences The Johns Hopkins University 3400 N. Charles St. Baltimore, MD 21218-2686

Solomon H. Snyder Department of Neuroscience

Welcome from the Director

Welcome to the Solomon H. Snyder Department of Neuroscience at Johns Hopkins University. The Department, founded in 1980 by brain science pioneer Sol Snyder, is one of the first Neuroscience Departments in the country. With 32 primary faculty, 4 adjunct faculty and 69 secondary faculty conducting research in all areas of neuroscience ranging from ...