NIH Data Science Distinguished Seminar Series: BRAIN/BD2K Seminar Towards Solutions to Experimental and Computational Challenges in Neuroscience Air date: Friday, August 14, 2015, 11:00:00 AM

Drs. Christof Koch and Emery Brown will describe the computational or experimental challenges associated with Big Data in their respective domains of neuroscience. From the basic to applied realms, science is being transformed by the collection of data on increasingly finer resolutions, both spatially and temporally. Storing, accessing, and analyzing these data create numerous challenges as well as opportunities.

Videocast

browser does not support iframe

Attending the seminar

This is a public event at the National Institutes of Health. All individuals interested in the seminar may attend. If this will be your first time visiting the NIH we strongly encourage you to review the visitor information at http://www.nih.gov/about/visitor/index.htm and allow extra time for security and transit. Individuals with disabilities who need Sign Language Interpreters and/or reasonable accommodation to participate in this event should contact Sonynka Ngosso, at (301) 402-9816. Requests should be made at least 5 business days in advance of the event.

Christof Koch, Ph.D.

Christof Koch, Ph.D is the President and Chief Scientific Officer of the Allen Institute for Brain Science. His research interests include elucidating the biophysical mechanisms underlying neural computation, understanding the mechanisms ...

There have been remarkable advances in understanding the brain, but how do you actually study the neurons inside it? Using gorgeous imagery, neuroscientist and TED Fellow Carl Schoonover shows the tools that let us see inside our brains.

Filmed February 2012 at TED 2012 Uploaded to YouTube on July 12, 2013 by TED

“Mind Reading Computer System May Help People with Locked-in Syndrome”

Boston University neuroscientist Frank Guenther works with the National Science Foundation’s Center of Excellence for Learning in Education, Science and Technology (CELEST), which is made up of eight private and public institutions. Its purpose is to synthesize the experimental modeling and technological approaches to research in order to understand how the brain learns as a whole system.

NSF BRAIN Initiative Science Nation – October 13, 2011

Description

Imagine living a life in which you are aware of the world around you but you’re prevented from engaging in it because you are completely paralyzed. Even speaking is impossible. For an estimated 50,000 Americans this is a harsh reality. It’s called locked-in syndrome, a condition in which people with normal cognitive brain activity suffer severe paralysis, often from injuries ...

Vincent Pieribone Profile

Professor of Cellular and Molecular Physiology and of Neurobiology, Yale University Fellow, John B. Pierce Laboratory

Dr Pieribone is developing genetically encoded fluorescent probes of membrane electrical potential. These probes allow one to use optical instruments (microscopes) to monitor the electrical activity of neurons. He has also engineered miniature imaging systems that can be head mounted on mammels and allow mobile recording of neuronal activity.

Video published on April 23, 2012 by Big Think

This lecture describes recent work on developing small microscopes for deep tissue imaging that can surgically implementing into living and awake animals. Exciting applications are described for imaging the activity and long term shape changes of single neurons in the brain.

Video published on Nov. 11, 2013 by iBioEducation

Mark Schnitzer Profile

Associate Professor of Biology and Applied Physics, Stanford HHMI Investigator Principal Investigator, Schnizer Group

Dr. Schnitzer has longstanding interests in neural circuit dynamics and optical imaging focusing on: the development and application of fiber-optic, micro-optic, and nanophotonic imaging techniques for studies of learning and memory; in vivo fluorescence imaging and behavioral studies of hippocampal-dependent cognition and learning; and development of high-throughput, massively parallel imaging techniques for studying brain function in Drosophila.

“How do we see neurons, the brain’s principal functional units? Discover new views made possible by Multi-photon microscopy.”

Part 1 of 12 featuring MIT Professors Elly Nedivi and Peter So.

Video published on Sept. 24, 2014 by EyeWire

Profile of Elly Nedivi

Professor of Brain & Cognitive Sciences and Biology, MIT Neuroscience Principal Investigator, Nedivi Lab

The Nedivi lab, part of the Picower Institute for Learning and Memory, studies the cellular mechanisms that underlie activity-dependent plasticity in the developing and adult brain through studies of neuronal structural dynamics, identification of the participating genes, and characterization of the proteins they encode.

Functional magnetic resonance imaging (fMRI) has revolutionized our understanding of the human brain, but the method is now approaching the limit of its capabilities. Alan Jasanoff hopes to break through this limit and to develop new technologies for imaging the molecular and cellular phenomena that underlie brain function.

Video published on Mar 9, 2010 by mittechtv

Profile

Associate Professor of Biological Engineering with appointments in Brain and Cognitive Sciences and Nuclear Science and Engineering, MIT Neuroscience Associate member of the McGovern Institute Principal Investigator, Jasanoff Lab

Functional magnetic resonance imaging (fMRI) has revolutionized our understanding of the human brain, but the method is now approaching the limit of its capabilities. Alan Jasanoff hopes to break through this limit and to develop new technologies for imaging the molecular and cellular phenomena that underlie brain function.

“The B.R.A.I.N. Initiative faces a major technological barrier in obtaining high resolution, real-time recordings of brain activity over large areas of the brain. Leading researchers will explore available and promising approaches to surmounting that barrier, exploring current work and future possibilities for the detection and recording of the range of relevant electrical and chemical signals in the nervous system.”

Presentation by Alan Jasanoff of Jasnoff Lab research Published on June 16, 2014 by Calit2ube

Lab Profile

Principal Investigator, Alan Jasanoff MIT Neuroscience

Jasanoff Lab is developing a new generation of functional magnetic resonance imaging (fMRI) methods to study the neural mechanisms of behavior.The Lab’s focus is on the design and application of new contrast agents that may help define spatiotemporal patterns of neural activity with far better precision and resolution than current techniques allow. Experiments using the new agents will combine the specificity of cellular neuroimaging with the whole brain coverage and noninvasiveness of conventional fMRI.