The Surprise Discovery Offers a New Understanding of the Disease

Scientists at The Scripps Research Institute (TSRI) have found diverse genomic changes in single neurons from the brains of Alzheimer’s patients, pointing to an unexpected factor that may underpin the most common form of the disease.

A new study shows Alzheimer’s brains commonly have many neurons with significantly more DNA and genomic copies of the Alzheimer’s-linked gene, APP, than normal brains.